September 12, 2022 Case of the Week

A presentation of diffuse abdominal pain and dysphagia.

Describe your macroscopic findings and the most likely diagnosis that tries it all together.

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Answer:

Gross hepatomegaly with multiple tan-white nodules. H&E sections show metastatic deposit of moderate-poorly differentiated squamous cell carcinoma. The primary tumor site was esophagus (note the esophageal stent in situ).